BiLevel-S therapy with lots of flexibility.

The prisma25S is the device of choice for patients with high, fluctuating pressure needs or poor CPAP compliance, suffering from obstructive, mixed, or complex sleep apnea. High flexibility in BiLevel settings, various automatic functions as well as process and comfort-supporting features enable safe, effective and quiet BiLevel-S therapy made in Germany.

made in germany loewenstein

The most important features.

The prisma25S sets new technical standards in its product class with numerous innovations. It features a large colorful touch display, intelligent trigger functions and optionally includes TriLevel, a clinically validated algorithm for maximum pressure reduction, ensuring optimal therapy outcomes. Efficient, safe for the patient and remarkably quiet.

When using the prismaAQUA humidifier, you can optionally add on smartAQUAcontrol: for a quick sensation of warmth in the airflow at the beginning of therapy and to ensure humidification performance during periods of increased leakage. The optional prismaAQUA humidifier can also be operated with a heated circuit.

The device features several BiLevel modes such as additional pressure relief (Bi soft 1/2), automatic pressure differential adjustment(autoPDIFF) and autoTriLevel. This allows for therapy adjustment according to the patient's needs, ensuring additional and safe breathing comfort.

The prisma25S impresses with its adaptive pressure control over a wide pressure range, apnea differentiation using Forced Oscillation Technique (FOT) and its process-supporting properties. A pressure range between 4 hPa and 25 hPa, along with numerous adjustment parameters provide greater flexibility in therapy settings.

Product features

Modern connectivity

Compatible and future-proof. Various interfaces such as SD, PSG, LAN and external modem offer various options for data transfer. Our software solutions (e.g. prismaTS, prisma APP and prisma CLOUD) are available for simple, flexible and secure therapy support.

Fall asleep comfortably - softSTART

The softSTART function can be activated to help you fall asleep and slowly acclimate to therapy pressure during the sleep phase. This ensures a slow increase in pressure over a set period until therapy pressure is reached. This is particularly useful for patients who find high pressure uncomfortable while awake and cannot fall asleep.


prismaAQUA is the powerful respiratory air humidifier for the world of sleep apnea therapy devices. It humidifies and warms the breathing air to prevent the patient's mucous membranes from drying out.

Pressure relief softPAP

For comfortable expiration during therapy, the pressure in CPAP and autoCPAP mode is reduced at the start of expiration and increased to therapy pressure in time for the start of the inhalation phase to facilitate exhalation as much as possible and effectively prevent events.

Deep sleep and respiratory stability indicators

During therapy, prisma RECOVER continuously analyzes the patient’s breathing pattern and recognizes the phases of stable respiration that indicate deep sleep, a particularly restorative sleep phase. In BiLevel modes too the phases of highly stable respiration are detected and reported. For the first time ever, this function can assess therapy success regarding to sleep quality in prisma JOURNAL, prismaTS or tele-monitoring with prisma CLOUD.

Effortless and consistent application

The combination of a large screen (touch, LED) and intelligent menu navigation makes operation intuitive and fast. It's the ideal support for your various work processes.


Visit our YouTube channel for informative tutorials, application examples and helpful tips on our product portfolio.

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prismaLINE setting up
prismaLINE adjusting therapy
prismaLINE therapy start and end
prismaLINE prismaAQUA

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